Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334263 | 0.88 | ESR1 (0.41) | ESR1ESR2TSHRNQO1ALDH1A1 | |
| SCHEMBL548702 | 0.84 | TSHR (0.41) | ESR1ESR2TSHRNQO1ALDH1A1 | |
| SCHEMBL1668678 | 0.81 | MEN1 (0.40) | ESR1ESR2TSHRALDH1A1ATM | |
| SCHEMBL6328901 | 0.79 | MEN1 (0.42) | ESR1ESR2NQO1ALDH1A1ATM | |
| SCHEMBL10946743 | 0.78 | CXCR5 (0.36) | ESR1ESR2ALDH1A1CA1CA2 | |
| SCHEMBL6336590 | 0.78 | MEN1 (0.45) | NQO1ALDH1A1ATMMEN1MAPT | |
| SCHEMBL6334758 | 0.78 | MEN1 (0.45) | NQO1ALDH1A1ATMMEN1MAPT | |
| SCHEMBL6327063 | 0.78 | MEN1 (0.45) | NQO1ALDH1A1ATMMEN1MAPT | |
| SCHEMBL156913 | 0.77 | TSHR (0.38) | ESR1ESR2TSHRALDH1A1ATM | |
| SCHEMBL2466445 | 0.76 | MEN1 (0.42) | TSHRALDH1A1ATMMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027274-A2 | COMPOSITIONS AND METHODS FOR IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-01 | — | — | WO | disclosed |