SCHEMBL548702

SCHEMBL548702

CCCC(CC)c1c(O)cccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
CXCR5 P32302 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
NQO1 P15559 1/20 0.36
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
ALDH1A1 P00352 2/20 0.34
ATM Q13315 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6334263 0.91 ESR1 (0.41) TSHRESR1ESR2HDAC4HDAC2
SCHEMBL2464579 0.88 LMNA (0.41) TSHRHDAC4HDAC2HDAC8CA2
SCHEMBL31545205 0.87 TSHR (0.46) TSHRESR1ESR2HDAC4HDAC2
SCHEMBL16054188 0.86 MEN1 (0.42) TSHRALDH1A1ATMMEN1MAPT
SCHEMBL725190 0.84 ESR1 (0.37) TSHRESR1ESR2HDAC4HDAC2
SCHEMBL1668678 0.84 MEN1 (0.40) TSHRESR1ESR2ALDH1A1ATM
SCHEMBL156913 0.84 TSHR (0.38) TSHRESR1ESR2HDAC4HDAC2
SCHEMBL6328901 0.82 MEN1 (0.42) ESR1ESR2NQO1ALDH1A1ATM
SCHEMBL6334758 0.81 MEN1 (0.45) NQO1ALDH1A1ATMMEN1MAPT
SCHEMBL6336590 0.81 MEN1 (0.45) NQO1ALDH1A1ATMMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144739-A1 A SKIN BRIGHTENING COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2026-05-28 US claimed
EP-4615399-B1 A SKIN BRIGHTENING COMPOSITION UNILEVER IP HOLDINGS B V (NL) 2026-05-20 EP claimed
WO-2026098831-A1 USE OF A PERSONAL CARE COMPOSITION FOR IMPROVING THE BARRIER FUNCTION OF SKIN UNILEVER IP HOLDINGS B.V. (NL) 2026-05-15 WO claimed
US-20260132356-A1 MILD WASH COMPOSITION WITH BIODEGRADABLE THICKENER AND ENHANCED MICROBIOTA IMPACT CONOPCO, INC., D/B/A UNILEVER (US) 2026-05-14 US claimed
US-12622861-B2 Stable wash composition CONOPCO, INC. (US) 2026-05-12 US claimed
EP-4593790-B1 MILD WASH COMPOSITION WITH BIODEGRADABLE THICKENER AND ENHANCED MICROBIOTA IMPACT UNILEVER IP HOLDINGS B V (NL) 2026-03-18 EP claimed
US-12576014-B2 Personal care composition with visually distinct aqueous and oil phase CONOPCO, INC. (US) 2026-03-17 US claimed
WO-2026041386-A1 ANHYDROUS COMPOSITION COMPRISING MONOESTERS AND MAINLY PETROLATUM UNILEVER IP HOLDINGS B.V. (NL) 2026-02-26 WO claimed
US-12533305-B2 Naturally derived surfactant system with polyglycerol esters and compositions comprising the same CONOPCO, INC. (US) 2026-01-27 US claimed
EP-3675806-B1 PERSONAL CARE COMPOSITION UNILEVER GLOBAL IP LTD (GB) 2026-01-21 EP claimed
WO-2004052329-A1 DI-SUBSTITUTED RESORCINOLS AS SKIN LIGHTENING AGENTS UNILEVER PLC (GB) 2004-06-24 WO claimed
US-20040109832-A1 Di-substituted resorcinols as skin lightening agents UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-06-10 US claimed
US-20030185773-A1 Stabilization of sunscreens in cosmetic compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-10-02 US claimed
US-20030185867-A1 Stabilization of terpenoids in cosmetic compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-10-02 US claimed
WO-2003080009-A1 STABILIZATION OF SUNSCREENS IN COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2003-10-02 WO claimed
WO-2003080011-A1 STABILIZATION OF TERPENOIDS IN COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2003-10-02 WO claimed
WO-2003080002-A1 STABILIZATION OF RESORCINOL DERIVATIVES IN COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2003-10-02 WO claimed
US-20030180234-A1 Stabilization of resorcinol derivatives in cosmetic compositions UNILEVER HOME & PERSONAL CARE USA, 2003-09-25 US claimed
WO-1999037172-A1 FRESH PRODUCE WASH FOR INCREASING SHELF LIFE HEALTH AND HYGIENE INTERNATIONAL PTY. LTD. (AU) 1999-07-29 WO claimed
US-4043947-A Impact improvement of rubber-modified nitrile resins STANDARD OIL COMPANY (US) 1977-08-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040109832-A1 Di-substituted resorcinols as skin lightening agents DECR1, RCOR1, RER1 TSHR 1856/4885ESR1 638/4885ESR2 223/4885
US-20030185773-A1 Stabilization of sunscreens in cosmetic compositions RCOR1, CBR1, NQO1 TSHR 2772/4885ESR1 1321/4885ESR2 1091/4885
US-12622861-B2 Stable wash composition ALG1, IL4, CUTA TSHR 3522/4885ESR1 4786/4885ESR2 4602/4885
US-20030180234-A1 Stabilization of resorcinol derivatives in cosmetic compositions RCOR1, RCOR3, MCOLN2 TSHR 1528/4885ESR1 1782/4885ESR2 1120/4885
US-20260144739-A1 A SKIN BRIGHTENING COMPOSITION CUTA, MYB, RBP4 TSHR 1103/4885ESR1 670/4885ESR2 404/4885
US-12533305-B2 Naturally derived surfactant system with polyglycerol esters and compositions comprising the same SGMS1, FFAR1, SGMS2 TSHR 2677/4885ESR1 4707/4885ESR2 3556/4885
US-20030185867-A1 Stabilization of terpenoids in cosmetic compositions SQLE, CYP51A1, RBP4 TSHR 3376/4885ESR1 1235/4885ESR2 1132/4885
US-12576014-B2 Personal care composition with visually distinct aqueous and oil phase CUTA, RBP4, RBP1 TSHR 1733/4885ESR1 2214/4885ESR2 1431/4885
US-20260132356-A1 MILD WASH COMPOSITION WITH BIODEGRADABLE THICKENER AND ENHANCED MICROBIOTA IMPACT WASHC4, MUC1, WASHC5 TSHR 2262/4885ESR1 4525/4885ESR2 4789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.