Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.38 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL2332415 | 1.00 | TP53 (0.65) | TP53FFAR3LCKFYNOR51E2 | |
| Lactic Acid SCHEMBL12505872 | 0.97 | TP53 (0.61) | TP53FFAR3LCKFYNOR51E2 | |
| Lactic Acid SCHEMBL3928098 | 0.94 | — | — | |
| Lactic Acid SCHEMBL8734273 | 0.92 | TP53 (0.55) | TP53FFAR3LCKFYNOR51E2 | |
| Lactic Acid SCHEMBL27546261 | 0.91 | TP53 (0.69) | TP53FFAR3OR51E2CHRM1AKR1A1 | |
| Lactic Acid SCHEMBL5697792 | 0.91 | TP53 (0.69) | TP53FFAR3OR51E2CHRM1AKR1A1 | |
| Lactic Acid SCHEMBL15313316 | 0.91 | TP53 (0.69) | TP53FFAR3OR51E2CHRM1AKR1A1 | |
| Succinic Acid SCHEMBL9714183 | 0.90 | TP53 (0.52) | TP53FFAR3HDAC1HDAC2GPR84 | |
| Lactic Acid SCHEMBL10691040 | 0.88 | TP53 (0.65) | TP53FFAR3OR51E2CHRM1AKR1A1 | |
| Succinic Acid SCHEMBL27552607 | 0.88 | TP53 (0.50) | TP53FFAR3OR51E2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609190-A2 | ANTIMICROBIAL METHOD FOR FERMENTATION PROCESSES | DeLaval Holding AB (SE) | 2013-07-03 | — | — | EP | disclosed |
| EP-2603612-A2 | FERMENTATION PROCESS FOR PRODUCING CHEMICALS | Vogelbusch GmbH (AT) | 2013-06-19 | — | — | EP | disclosed |
| WO-2013064682-A2 | FERMENTATION PROCESS FOR PRODUCING CHEMICALS | VOGELBUSCH GMBH (AT) | 2013-05-10 | — | — | WO | disclosed |
| WO-2012027469-A2 | ANTIMICROBIAL METHOD FOR FERMENTATION PROCESSES | DELAVAL HOLDING AB (SE) | 2012-03-01 | — | — | WO | disclosed |
| WO-2010059616-A2 | BIOCATALYSTS AND METHODS FOR CONVERSION OF HEMICELLULOSE HYDROLSATES TO BIOBASED PRODUCTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-05-27 | — | — | WO | disclosed |