Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | APEX1 | P27695 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxolinic Acid SCHEMBL28034345 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL29420856 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL637058 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL24445 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL27985461 | 0.86 | KDM4E (0.97) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11669157 | 0.86 | ALDH1A1 (0.75) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL30829037 | 0.86 | KDM4E (0.97) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL27472871 | 0.86 | KDM4E (0.97) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL3467839 | 0.86 | KDM4E (0.97) | KDM4EALDH1A1CYP1A2CYP2D6HPGD | |
| Oxolinic Acid SCHEMBL28034329 | 0.86 | KDM4E (0.97) | KDM4EALDH1A1CYP1A2CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | claimed |
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | disclosed |