Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.78 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | DRD5 | P21918 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113648 | 0.94 | HTR6 (0.81) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7114790 | 0.91 | HTR6 (0.77) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7114786 | 0.91 | HTR6 (0.77) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7256045 | 0.90 | HTR6 (0.63) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7119070 | 0.89 | HTR6 (0.88) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7122467 | 0.89 | HTR6 (0.77) | HTR6 | |
| SCHEMBL7122465 | 0.89 | HTR6 (0.77) | HTR6 | |
| SCHEMBL7116714 | 0.88 | HTR6 (0.83) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7118984 | 0.88 | HTR6 (0.76) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7118985 | 0.88 | HTR6 (0.76) | HTR6DRD2DRD4DRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029239-A1 | CHROMAN AND BENZOFURAN DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2003-04-10 | — | — | WO | claimed |