Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249120 | 1.00 | MMP2 (0.47) | MMP2NPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3591352 | 0.86 | MMP2 (0.51) | MMP2NPSR1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL12861953 | 0.85 | MMP2 (0.50) | MMP2NPSR1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL13151965 | 0.82 | GAA (0.47) | MMP2NPSR1ALDH1A1MAPTGAA | |
| SCHEMBL10076669 | 0.82 | GAA (0.47) | MMP2NPSR1ALDH1A1MAPTGAA | |
| SCHEMBL8695430 | 0.82 | GAA (0.47) | MMP2NPSR1ALDH1A1MAPTGAA | |
| SCHEMBL10076668 | 0.82 | GAA (0.47) | MMP2NPSR1ALDH1A1MAPTGAA | |
| SCHEMBL11973569 | 0.80 | MMP2 (0.59) | MMP2NPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6981947 | 0.80 | MMP2 (0.59) | MMP2NPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13167999 | 0.80 | TSHR (0.57) | MMP2NPSR1ALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573387-B1 | Synthesis of α,β-substituted amino amides, esters, and acids | THE SCRIPPS RESEARCH INSTITUTE | 2003-06-03 | — | — | US | disclosed |