SCHEMBL7253177

SCHEMBL7253177

Brc1cscc1-c1cscc1Br

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332154 0.81
SCHEMBL25028117 0.72
SCHEMBL2037998 0.72 ESR1 (0.71) ESR1ESR2
SCHEMBL3678137 0.71 ESR1 (0.42) ESR1ESR2
SCHEMBL6050657 0.69 DAO (0.31)
SCHEMBL6050649 0.68 PTGS2 (0.56) ESR1ESR2
SCHEMBL14303468 0.67
SCHEMBL28235 0.67
SCHEMBL9665410 0.67
SCHEMBL9672997 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113189175-B Preparation method of molecular imprinting sensor, and product and application obtained by preparation method 南京大学 2023-07-28 CN disclosed
CN-103113387-B The synthetic method of asymmetric two thieno-heteroaromatic compounds HENAN UNIVERSITY (CN) 2016-02-17 CN disclosed
CN-103113387-A Synthesis method of asymmetrical dithieno heteroaromatic compounds UNIV HENAN 2013-05-22 CN disclosed
US-6515144-B2 In the form of a helix which contains five-membered rings unsaturated heterocycles that are cross-conjugated and annelated into a helix THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2003-02-04 US disclosed
US-20020193611-A1 OLIGOTHIOPHENES AND SYNTHESIS THEREOF NATIONAL SCIENCE FOUNDATION 2002-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193611-A1 OLIGOTHIOPHENES AND SYNTHESIS THEREOF OR51E2, WEE2, FARS2 ESR1 1663/4885ESR2 1412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.