Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603763 | 0.78 | TSHR (0.39) | — | |
| SCHEMBL908901 | 0.77 | — | — | |
| SCHEMBL908377 | 0.77 | — | — | |
| SCHEMBL5600868 | 0.74 | MAPT (0.32) | KDM4EGAA | |
| SCHEMBL5600756 | 0.69 | POLB (0.33) | — | |
| SCHEMBL5601257 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL5601434 | 0.67 | CSNK1E (0.35) | KDM4E | |
| SCHEMBL5601440 | 0.67 | CSNK1E (0.35) | KDM4E | |
| SCHEMBL5603832 | 0.67 | CSNK1E (0.35) | KDM4E | |
| SCHEMBL5602687 | 0.67 | CSNK1E (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053941-A2 | BARBITURIC ACID DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND/OR MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |
| WO-2003040103-A1 | β-SULFONE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-α CONVERTING ENZYME (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-05-15 | — | — | WO | disclosed |