Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070975 | 0.91 | GAA (0.39) | GAAHPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL25285902 | 0.87 | BAZ2B (0.47) | GAAHPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL7250626 | 0.87 | LMNA (0.36) | GAAHPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL31468720 | 0.86 | TSHR (0.34) | HPGDMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4067527 | 0.86 | NOTUM (0.36) | HPGDMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29189448 | 0.84 | MAPT (0.41) | GAAHPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL25243907 | 0.84 | POLB (0.32) | GAAHPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL29189461 | 0.84 | GAA (0.33) | GAAHPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL25480941 | 0.84 | GAA (0.35) | GAAHPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL29148286 | 0.84 | LMNA (0.35) | HPGDMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603147-A | N-phenyl triazinone derivative and preparation method and application thereof | 贵州大学 | 2024-02-27 | — | — | CN | disclosed |
| US-6602825-B1 | Cyclization of an isocyanate with a thiourea and carbonic acid | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-05 | — | — | US | disclosed |