SCHEMBL7253278

SCHEMBL7253278

COCC(C)(N)c1ccccc1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43
CA14 Q9ULX7 1/20 0.43
ALDH1A1 P00352 3/20 0.41
ADRA2B P18089 1/20 0.41
PTGS1 P23219 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CASR P41180 1/20 0.40
IDO1 P14902 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
GAA P10253 2/20 0.37
MAPT P10636 1/20 0.37
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
APP P05067 1/20 0.36
CTSD P07339 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16487251 0.83 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL4934040 0.79 AOC3 (0.40) CA1CA2CA7CA9CA12
SCHEMBL4631777 0.78 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL3205223 0.75 CASR (0.50) CA1CA2CA7CA9CA12
SCHEMBL3978964 0.75 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL19468259 0.73 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL8784464 0.73 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL29771456 0.73 CA2 (0.57) CA1CA2CA7CA9CA12
SCHEMBL9326106 0.73 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL30948566 0.73 CA1 (0.57) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003014113-A1 NOVEL BENZOPYRAN COMPOUNDS AND PROCESS FOR THEIR PREPARATION AND USE GLENMARK PHARMACEUTICALS LIMITED (IN) 2003-02-20 WO disclosed