Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 9/20 | 0.64 |
| ▸ | WNT3A | P56704 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13715357 | 0.89 | ATM (0.70) | CTNNB1WNT3AALDH1A1HPGDKDM4E | |
| SCHEMBL29458253 | 0.85 | MEN1 (0.76) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL2237626 | 0.85 | MEN1 (0.76) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL6486626 | 0.84 | CTNNB1 (0.66) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL4865452 | 0.84 | CTNNB1 (0.66) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL22651304 | 0.83 | CTNNB1 (0.69) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL1092123 | 0.82 | ATM (0.81) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL4258312 | 0.82 | CTNNB1 (0.64) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL2843731 | 0.82 | CTNNB1 (0.64) | CTNNB1WNT3AALDH1A1MAPK1MEN1 | |
| SCHEMBL13785040 | 0.82 | CTNNB1 (0.64) | CTNNB1WNT3AALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003030909-A1 | 2- AND 4-AMINOPYRIMIDINES N-SUBSTTITUDED BY A BICYCLIC RING FOR USE AS KINASE INHIBITORS IN THE TREATMENT OF CANCER | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-17 | — | — | WO | disclosed |