Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 11/20 | 0.69 |
| ▸ | WNT3A | P56704 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22638726 | 0.90 | CTNNB1 (0.72) | CTNNB1WNT3AALDH1A1HPGDPKM | |
| SCHEMBL7385092 | 0.89 | ALDH1A1 (0.64) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL175424 | 0.86 | CTNNB1 (0.64) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL10961709 | 0.85 | CTNNB1 (0.71) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL15979947 | 0.84 | CTNNB1 (0.83) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL10733692 | 0.83 | CTNNB1 (0.69) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL3924051 | 0.83 | HPGD (0.82) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL31490470 | 0.83 | HPGD (0.82) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL7253369 | 0.83 | CTNNB1 (0.64) | CTNNB1WNT3AALDH1A1HPGDMAOB | |
| SCHEMBL29458253 | 0.82 | MEN1 (0.76) | CTNNB1WNT3AALDH1A1HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224396-A1 | COMPOUNDS INHIBITING TDG ACTIVITY | 上海仕谱生物科技有限公司 | 2020-11-12 | — | — | WO | disclosed |