Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253488 | 0.88 | ABCB1 (0.48) | ABCB1KCNA5 | |
| Hydrochloric Acid SCHEMBL11609080 | 0.75 | ABCB1 (0.59) | ABCB1KCNE1KCNQ1 | |
| Hydrochloric Acid SCHEMBL11609075 | 0.75 | ABCB1 (0.59) | ABCB1KCNE1KCNQ1 | |
| SCHEMBL7256921 | 0.74 | ABCB1 (0.48) | ABCB1SIGMAR1KCNE1KCNQ1 | |
| SCHEMBL7257087 | 0.70 | MEN1 (0.48) | L3MBTL1MEN1KMT2AALDH1A1KCNA5 | |
| SCHEMBL10445891 | 0.69 | ABCB1 (0.51) | ABCB1MAPK1KCNE1KCNQ1 | |
| SCHEMBL7253231 | 0.68 | ABCB1 (0.68) | ABCB1KCNA5KCNE1KCNQ1 | |
| SCHEMBL7256886 | 0.68 | ABCB1 (0.38) | ABCB1ALDH1A1KCNA5KCNE1KCNQ1 | |
| SCHEMBL7253762 | 0.66 | ABCB1 (0.53) | ABCB1KCNA5KCNE1KCNQ1 | |
| SCHEMBL7258463 | 0.66 | ABCB1 (0.45) | ABCB1SIGMAR1KCNA5KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003014113-A1 | NOVEL BENZOPYRAN COMPOUNDS AND PROCESS FOR THEIR PREPARATION AND USE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2003-02-20 | — | — | WO | claimed |
| WO-2003014113-A1 | NOVEL BENZOPYRAN COMPOUNDS AND PROCESS FOR THEIR PREPARATION AND USE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2003-02-20 | — | — | WO | disclosed |