Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13767833 | 0.81 | ABCB1 (0.47) | ABCB1KCNE1KCNQ1ABCC9MAPK1 | |
| SCHEMBL10917581 | 0.81 | ABCB1 (0.50) | ABCB1KCNE1KCNQ1ABCC9MAPK1 | |
| Hydrochloric Acid SCHEMBL11609075 | 0.81 | ABCB1 (0.59) | ABCB1KCNE1KCNQ1ABCC9 | |
| Hydrochloric Acid SCHEMBL11609080 | 0.81 | ABCB1 (0.59) | ABCB1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10917584 | 0.81 | ABCB1 (0.50) | ABCB1KCNE1KCNQ1ABCC9MAPK1 | |
| SCHEMBL10917589 | 0.81 | ABCB1 (0.50) | ABCB1KCNE1KCNQ1ABCC9MAPK1 | |
| SCHEMBL7253231 | 0.79 | ABCB1 (0.68) | ABCB1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10446102 | 0.79 | ABCB1 (0.46) | ABCB1KCNE1KCNQ1ABCC9MAPK1 | |
| SCHEMBL21408674 | 0.78 | KCNE1 (0.51) | ABCB1KCNE1KCNQ1ABCC9MAOA | |
| SCHEMBL9363850 | 0.78 | ABCC9 (0.47) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401010-A2 | Pyranyl cyanoguanidine derivatives | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | disclosed |