Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.42 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 3/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257914 | 0.86 | TRPV1 (0.48) | CNR2CNR1TRPV1CPT1ACPT1B | |
| SCHEMBL7255176 | 0.86 | CNR2 (0.46) | CNR2CNR1MGAMGAASI | |
| SCHEMBL7257573 | 0.78 | CNR2 (0.45) | CNR2CNR1SMN1; SMN2HSD11B1 | |
| SCHEMBL7257577 | 0.77 | CNR2 (0.47) | CNR2CNR1TRPV1CPT1ACPT1B | |
| SCHEMBL7257521 | 0.77 | CNR2 (0.48) | CNR2CNR1SMN1; SMN2GAA | |
| SCHEMBL7255168 | 0.77 | CNR2 (0.44) | CNR2CNR1MGAMGAASI | |
| SCHEMBL7254992 | 0.76 | CNR2 (0.48) | CNR2CNR1CPT1ACPT1BCPT2 | |
| SCHEMBL5442734 | 0.73 | CNR2 (0.48) | CNR2CNR1LMNASMN1; SMN2GAA | |
| SCHEMBL7257536 | 0.71 | MAOB (0.41) | CNR2LMNA | |
| SCHEMBL13807213 | 0.70 | GPR119 (0.47) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003062232-A1 | DERIVATIVES OF THIAZOLES USED FOR THE TREATMENT OF NEUROLOGICAL DISEASES | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-07-31 | — | — | WO | disclosed |