SCHEMBL7254307

SCHEMBL7254307

CS(=O)(=O)c1ccc(-c2ccoc(=O)c2Oc2ccc(F)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 11/20 0.55
PTGS1 P23219 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7257818 0.81 PTGS1 (0.41) PTGS2PTGS1
SCHEMBL7254185 0.81 PTGS2 (0.68) PTGS2PTGS1
SCHEMBL7254203 0.77 PTGS2 (0.62) PTGS2
SCHEMBL7363510 0.74 SOS1 (0.66) PTGS2PTGS1
SCHEMBL8484099 0.73 PTGS2 (0.81) PTGS2PTGS1
SCHEMBL4183493 0.73 PTGS2 (0.59) PTGS2PTGS1
SCHEMBL4191114 0.73 PTGS2 (0.67) PTGS2PTGS1
SCHEMBL1375790 0.71 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL4190408 0.71 PTGS2 (0.63) PTGS2PTGS1
SCHEMBL7257843 0.70 PTGS2 (0.56) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003006451-A1 4-PHENYLPYRAN-2-ONE DERIVATIVES ALMIRALL PRODESFARMA S.A. (ES) 2003-01-23 WO disclosed