SCHEMBL7254333

SCHEMBL7254333

CCCCCBr.CCCCCCN1CCC(CNC(=O)c2cc(Cl)c(N)[nH]c2=O)CC1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 8/20 0.47
NR4A2 P43354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7258023 1.00 HTR4 (0.47) HTR4NR4A2
SCHEMBL6328192 0.95 HTR4 (0.51) HTR4NR4A2
SCHEMBL6329818 0.95 HTR4 (0.51) HTR4NR4A2
SCHEMBL14258189 0.92 NR4A2 (0.53) HTR4NR4A2
Hydrochloric Acid SCHEMBL6326593 0.91 NR4A2 (0.52) HTR4NR4A2
N-Propyl Bromide SCHEMBL7255030 0.90 HTR4 (0.46) HTR4NR4A2
SCHEMBL7257589 0.90 HTR4 (0.49) HTR4
SCHEMBL6335673 0.88 HTR4 (0.49) HTR4NR4A2
SCHEMBL7259539 0.88 HTR4 (0.51) HTR4
SCHEMBL7259053 0.87 HTR4 (0.46) HTR4NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003057688-A2 OXO OR OXY-PYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR MODULATORS PFIZER JAPAN INC. (JP) 2003-07-17 WO disclosed