Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SERPINH1 | P50454 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258556 | 0.84 | SERPINH1 (0.56) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL7258520 | 0.84 | MAPT (0.54) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL7254885 | 0.84 | SERPINH1 (0.59) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL7254911 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL7607272 | 0.79 | MAPT (0.62) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL7254895 | 0.76 | ALDH1A1 (0.50) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL7255037 | 0.74 | ALDH1A1 (0.48) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL7254788 | 0.74 | ALDH1A1 (0.60) | MAPTALDH1A1MAPK1NPSR1HPGD | |
| SCHEMBL7255056 | 0.72 | ALDH1A1 (0.52) | MAPTALDH1A1MAPK1NPSR1TDP1 | |
| SCHEMBL396186 | 0.71 | SLC6A4 (0.54) | MAPTALDH1A1MAPK1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029188-A2 | BETA-SUBSTITUTED NITROSTYRENE AND CYANOSTYRENE COMPOUNDS AND THEIR USE AS NEMATICIDES AND FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-10 | — | — | WO | claimed |
| WO-2003029188-A2 | BETA-SUBSTITUTED NITROSTYRENE AND CYANOSTYRENE COMPOUNDS AND THEIR USE AS NEMATICIDES AND FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-10 | — | — | WO | disclosed |