SCHEMBL7255182

SCHEMBL7255182

CSCCC(NC(=O)c1ccc(-c2ccc(N(C(c3cnc[nH]3)C(c3ccccc3)(c3ccccc3)c3ccccc3)S(=O)(=O)c3ccccc3)cc2)o1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 10/20 0.43
FNTB P49356 10/20 0.43
ALDH1A1 P00352 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PGGT1B P53609 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255934 0.95 FNTA (0.42) FNTAFNTB
SCHEMBL7260923 0.84 KDM4E (0.38) FNTAALDH1A1PGGT1B
SCHEMBL7258691 0.84 ALDH1A1 (0.39) FNTAALDH1A1NPSR1PGGT1B
SCHEMBL7255297 0.81 FNTA (0.52) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL7260755 0.81 ALDH1A1 (0.46) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL7255034 0.76 FNTA (0.43) FNTAFNTBALDH1A1NPSR1
SCHEMBL7258579 0.71 FNTA (0.55) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL7258722 0.70 FNTA (0.58) FNTAFNTBPGGT1B
SCHEMBL6759221 0.68 MEN1 (0.39) FNTAFNTB
SCHEMBL7260790 0.65 FNTA (0.59) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099812-A1 PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE PIERRE FABRE MEDICAMENT (FR) 2003-12-04 WO disclosed