SCHEMBL7255223

SCHEMBL7255223

CSCCC(NC(=O)c1ccc(-c2ccc(NCc3cncn3Cc3ccccc3)cc2)o1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 13/20 0.71
FNTB P49356 13/20 0.71
ALDH1A1 P00352 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7259759 0.94 FNTA (0.62) FNTAFNTB
SCHEMBL7259787 0.92 FNTA (0.72) FNTAFNTB
SCHEMBL7255031 0.85 FNTA (0.65) FNTAFNTB
SCHEMBL7255091 0.82 FNTA (0.68) FNTAFNTB
SCHEMBL7258579 0.80 FNTA (0.55) FNTAFNTBALDH1A1NPSR1
SCHEMBL7258722 0.77 FNTA (0.58) FNTAFNTB
SCHEMBL7255876 0.77 FNTA (0.64) FNTAFNTBALDH1A1NPSR1
SCHEMBL7255071 0.76 FNTA (0.48) FNTAFNTB
SCHEMBL7259636 0.76 FNTA (0.64) FNTAFNTB
SCHEMBL7255103 0.75 FNTA (0.65) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099812-A1 PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE PIERRE FABRE MEDICAMENT (FR) 2003-12-04 WO disclosed