SCHEMBL7259787

SCHEMBL7259787

CSCCC(NC(=O)c1ccc(-c2ccc(NCc3cncn3Cc3ccc(C#N)cc3)cc2)o1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 17/20 0.72
FNTB P49356 17/20 0.72
PGGT1B P53609 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255031 0.94 FNTA (0.65) FNTAFNTBPGGT1B
SCHEMBL7255223 0.92 FNTA (0.71) FNTAFNTB
SCHEMBL7255091 0.87 FNTA (0.68) FNTAFNTBPGGT1B
SCHEMBL7259759 0.86 FNTA (0.62) FNTAFNTBPGGT1B
SCHEMBL7255876 0.85 FNTA (0.64) FNTAFNTBPGGT1B
SCHEMBL7255179 0.84 FNTA (0.57) FNTAFNTBPGGT1B
SCHEMBL7259636 0.84 FNTA (0.64) FNTAFNTBPGGT1B
SCHEMBL7259778 0.83 FNTA (0.59) FNTAFNTBPGGT1B
SCHEMBL7258722 0.83 FNTA (0.58) FNTAFNTBPGGT1B
SCHEMBL7258776 0.82 FNTA (0.55) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099812-A1 PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE PIERRE FABRE MEDICAMENT (FR) 2003-12-04 WO claimed
WO-2003099812-A1 PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE PIERRE FABRE MEDICAMENT (FR) 2003-12-04 WO disclosed