Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260135 | 1.00 | AKR1B1 (0.65) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL7255650 | 0.94 | — | — | |
| SCHEMBL7255386 | 0.91 | ADAMTS5 (0.66) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL7259941 | 0.91 | ADAMTS5 (0.66) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL7255441 | 0.91 | ADAMTS5 (0.66) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL7260045 | 0.91 | ADAMTS5 (0.66) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL7255382 | 0.91 | ADAMTS5 (0.66) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL5213971 | 0.88 | ADAMTS5 (0.82) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL5213973 | 0.88 | ADAMTS5 (0.82) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL7255340 | 0.87 | AKR1B1 (0.68) | AKR1B1PTPN1ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070239-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | claimed |
| WO-2003070239-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | disclosed |