SCHEMBL7255343

SCHEMBL7255343

CC(=O)NC[C@H]1CN(c2ccc(C3CCN(Cc4cccs4)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.57
MAOB P27338 5/20 0.57
PTGS1 P23219 2/20 0.56
SDHA P31040 2/20 0.56
LMNA P02545 1/20 0.56
CALML3 P27482 1/20 0.56
F10 P00742 2/20 0.53
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255346 1.00 MAOA (0.57) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7259869 0.93 F10 (0.52) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7259865 0.93 F10 (0.52) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7256173 0.90 F10 (0.49) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7256177 0.90 F10 (0.49) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7258666 0.88 F10 (0.48) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7258668 0.88 F10 (0.48) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7258746 0.86 MAOA (0.56) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7258740 0.86 MAOA (0.56) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7259720 0.85 MAOA (0.56) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003097640-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) 2003-11-27 WO claimed
WO-2003097640-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) 2003-11-27 WO disclosed