Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434111 | 0.90 | PTGER1 (0.42) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL1158253 | 0.88 | CHRM2 (0.45) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| Hydrochloric Acid SCHEMBL16166428 | 0.87 | CHRM2 (0.45) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL724700 | 0.87 | ADRB2 (0.39) | PTGER1PTGER4PTGER3PTGER2ADRB2 | |
| SCHEMBL7755007 | 0.87 | ADRB2 (0.41) | PTGER1PTGER4PTGER3PTGER2ADRB2 | |
| SCHEMBL3772824 | 0.85 | ADRB2 (0.40) | PTGER1PTGER4PTGER3PTGER2ADRB2 | |
| SCHEMBL11301932 | 0.85 | ADRB2 (0.38) | PTGER1ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL4660356 | 0.82 | ESR1 (0.35) | PTGER1PTGER4PTGER3PTGER2ADRB2 | |
| SCHEMBL3721174 | 0.80 | IGF1R (0.39) | PTGER1PTGER4PTGER3PTGER2ADRA1A | |
| SCHEMBL7755565 | 0.78 | SLC6A2 (0.41) | ADRB2KMT2APOLBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025941-A2 | PROCESSES FOR THE PREPARATION OF FESOTERODINE | CADILA HEALTHCARE LIMITED (IN) | 2012-03-01 | — | — | WO | disclosed |