SCHEMBL7255391

SCHEMBL7255391

N#Cc1ccc(Cn2cncc2CN(CC2CCCCC2)c2ccc(-c3ccc(C(=O)O)o3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 13/20 0.48
FNTB P49356 13/20 0.48
PGGT1B P53609 6/20 0.43
CYP11B1 P15538 3/20 0.43
CYP11B2 P19099 3/20 0.43
KCNH2 Q12809 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255164 0.92 CYP11B1 (0.47) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7255055 0.88 CYP11B1 (0.42) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7260759 0.86 FNTA (0.45) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7255257 0.86 FNTA (0.46) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7258776 0.85 FNTA (0.55) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7255374 0.84 FNTA (0.45) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7260812 0.83 FNTA (0.57) FNTAFNTBCYP11B1CYP11B2
SCHEMBL7255356 0.79 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL7255069 0.78 CYP11B1 (0.49) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL6708558 0.78 KCNH2 (0.46) FNTAFNTBPGGT1BCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099812-A1 PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE PIERRE FABRE MEDICAMENT (FR) 2003-12-04 WO claimed