SCHEMBL7255668

SCHEMBL7255668

CC1(C)COC(c2cccc(O)c2)OC1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
DRD3 P35462 6/20 0.43
DRD2 P14416 4/20 0.43
MEN1 O00255 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
OPRD1 P41143 2/20 0.40
OPRK1 P41145 1/20 0.40
HTR1A P08908 1/20 0.38
DRD1 P21728 1/20 0.38
DRD4 P21917 1/20 0.38
DRD5 P21918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9946117 0.81 KMT2A (0.44) NPC1RAB9ASMN1; SMN2MEN1CYP2C19
SCHEMBL1135239 0.80 DRD3 (0.53) DRD3DRD2
SCHEMBL31125349 0.80 DRD3 (0.53) DRD3DRD2
SCHEMBL3105747 0.79 KDM1A (0.43) NPC1RAB9ASMN1; SMN2DRD3DRD2
SCHEMBL22436585 0.79 SMN1; SMN2 (0.42) NPC1RAB9ASMN1; SMN2DRD3DRD2
SCHEMBL19923127 0.78 SMN1; SMN2 (0.58) NPC1RAB9ASMN1; SMN2MEN1CYP2C19
SCHEMBL8608558 0.77 MEN1 (0.69) NPC1RAB9ASMN1; SMN2MEN1CYP2C19
SCHEMBL28553514 0.77 CA12 (0.41) DRD3DRD2OPRD1OPRK1DRD4
SCHEMBL7388541 0.77 DRD3 (0.50) SMN1; SMN2DRD3DRD2
SCHEMBL334828 0.76 MEN1 (0.40) NPC1RAB9ASMN1; SMN2MEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003070714-A1 FLUOROUS ACETYLATION UNISEARCH LIMITED (AU) 2003-08-28 WO claimed