Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.51 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.51 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18119744 | 0.89 | SMN1; SMN2 (0.62) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL15890432 | 0.88 | MEN1 (0.55) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL13701306 | 0.84 | MEN1 (0.50) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL18119746 | 0.83 | SMN1; SMN2 (0.57) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL764123 | 0.82 | CYP2C19 (1.00) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL22160331 | 0.81 | SMN1; SMN2 (0.64) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL11460056 | 0.81 | SMN1; SMN2 (0.56) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL9876533 | 0.80 | MEN1 (0.60) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL18119745 | 0.80 | SMN1; SMN2 (0.54) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL9778599 | 0.80 | RAB9A (0.48) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686621-A | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases | ALCON LABORATORIES, INC. (US) | 1997-11-11 | — | — | US | claimed |
| WO-1994004143-A1 | SUBSTITUTED HYDRINDANES FOR THE TREATMENT OF ANGIOGENESIS-DEPENDENT DISEASES | ALCON LABORATORIES, INC. (US) | 1994-03-03 | — | — | WO | claimed |
| US-4304921-A | Method of preparing β-halo esters from cyclic acetals | VANDERBILT UNIVERSITY (US) | 1981-12-08 | — | — | US | claimed |
| EP-2939997-B1 | POLYETHER DIOL AND METHOD FOR PRODUCING THE SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-12-05 | — | — | EP | disclosed |
| CN-104884418-B | Polyether diol and process for producing the same | 三菱瓦斯化学株式会社 | 2017-12-01 | — | — | CN | disclosed |
| US-9790155-B2 | Polyether diol and method for producing the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20150329454-A1 | POLYETHER DIOL AND METHOD FOR PRODUCING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-11-19 | — | — | US | disclosed |
| EP-2939997-A1 | POLYETHER DIOL AND METHOD FOR PRODUCING THE SAME | Mitsubishi Gas Chemical Company, Inc. (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-8962721-B2 | Nucleating agents for polyolefins based on acetal compounds | RELIANCE INDUSTRIES LIMITED (IN) | 2015-02-24 | — | — | US | disclosed |
| US-20130116366-A1 | NOVEL NUCLEATING AGENTS FOR POLYOLEFINS BASED ON ACETAL COMPOUNDS | RELIANCE INDUSTRIES LIMITED (IN) | 2013-05-09 | — | — | US | disclosed |
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-5780687-A | REACTING 1,3-DIOXANES WITH HYDROGEN IN PRESENCE OF HYDROGENATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0810202-A2 | Process for the preparation of 4-oxaamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| EP-0810194-A1 | Process for preparing 3-oxyalkylpropan-1-ols | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| US-5686621-A | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases | ALCON LABORATORIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5464866-A | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases | ALCON LABORATORIES, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1994004143-A1 | SUBSTITUTED HYDRINDANES FOR THE TREATMENT OF ANGIOGENESIS-DEPENDENT DISEASES | ALCON LABORATORIES, INC. (US) | 1994-03-03 | — | — | WO | disclosed |
| EP-0199210-B1 | CONVERSION OF 1,3-DIOXANES INTO 4-OXA-ALDEHYDES | BASF Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4324921-A | CATALYTIC ISOMERIZATION OF 5,5-DIMETHYL-1,3-DIOXANS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-4198323-A | 2,2,5-Trimethyl-5-phenyl-1,3-dioxane and perfume compositions containing it | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MEN1 4590/4885KMT2A 4328/4885CYP2C19 3767/4885 |
| US-20150329454-A1 | POLYETHER DIOL AND METHOD FOR PRODUCING THE SAME | DHCR7, HSD17B7, HSD17B12 | MEN1 1319/4885KMT2A 1683/4885CYP2C19 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.