Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338405 | 1.00 | PDE4A (0.64) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL16280148 | 1.00 | PDE4A (0.64) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL20591201 | 1.00 | PDE4A (0.64) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL13518379 | 1.00 | PDE4A (0.64) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL15121487 | 1.00 | PDE4A (0.64) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL5077868 | 1.00 | PDE4A (0.64) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL15121486 | 1.00 | PDE4A (0.64) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL28350552 | 0.98 | PDE4A (0.67) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL8343201 | 0.98 | PDE4A (0.67) | PDE4ALMNATDP1L3MBTL1USP2 | |
| SCHEMBL29356160 | 0.98 | PDE4A (0.67) | PDE4ALMNATDP1L3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9157105-B2 | Biosynthesis of CMP-legionaminic acid from fructose-6-P, and respective pathway intermediates, using novel GDP-linked precursors | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2015-10-13 | — | — | US | disclosed |
| US-20120052532-A1 | BIOSYNTHESIS OF CMP-LEGIONAMINIC ACID FROM FRUCTOSE-6-P, AND RESPECTIVE PATHWAY INTERMEDIATES, USING NOVEL GDP-LINKED PRECURSORS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2012-03-01 | — | — | US | disclosed |