SCHEMBL8343201

SCHEMBL8343201

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nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.67
LMNA P02545 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
USP2 O75604 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
KDM4E B2RXH2 2/20 0.38
OR51E2 Q9H255 1/20 0.35
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28350552 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL29356160 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL17144675 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL6407 1.00 PDE4A (0.67) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL10338405 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL15121486 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL15121487 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL5077868 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL725570 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL20591201 0.98 PDE4A (0.64) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118576621-A Application of fullerene nanomaterial targeting mannose receptor in preparation of medicine for treating liver steatosis 中国科学院化学研究所 2024-09-03 CN claimed
CN-118579765-A Fullerene nano material targeting mannose receptor and preparation method thereof 中国科学院化学研究所 2024-09-03 CN claimed
CN-105820272-A Perylene bisimide-cyclodextrin-sugar light dynamic compound and preparation method and application thereof 河北大学 2016-08-03 CN claimed
CN-119950752-A Protein nanoparticle with deformability and double targeting capability in response to pH, and preparation method and application thereof 武汉大学 2025-05-09 CN disclosed
CN-118579765-A Fullerene nano material targeting mannose receptor and preparation method thereof 中国科学院化学研究所 2024-09-03 CN disclosed
CN-118576621-A Application of fullerene nanomaterial targeting mannose receptor in preparation of medicine for treating liver steatosis 中国科学院化学研究所 2024-09-03 CN disclosed
CN-105820272-A Perylene bisimide-cyclodextrin-sugar light dynamic compound and preparation method and application thereof 河北大学 2016-08-03 CN disclosed
WO-1999010359-A2 LIPOSOMIC BASED SIALYL LEWIS X MIMETICS NOVARTIS AG (CH) 1999-03-04 WO disclosed
US-5837862-A Sialyl Lewis X mimetics incorporating mannopeptides THE SCRIPPS RESEARCH INSTITUTE (US) 1998-11-17 US disclosed