Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.79 |
| ▸ | MCHR2 | Q969V1 | 3/20 | 0.79 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.65 |
| ▸ | RAF1 | P04049 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NAMPT | P43490 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151139 | 0.91 | POLB (0.70) | MCHR1MCHR2POLBMEN1KMT2A | |
| SCHEMBL14430677 | 0.85 | CHRM4 (0.62) | MCHR1MCHR2POLBNAMPTGLA | |
| SCHEMBL6110214 | 0.83 | MCHR1 (0.90) | MCHR1MCHR2RAF1 | |
| SCHEMBL6368857 | 0.82 | MCHR1 (1.00) | MCHR1MCHR2RAF1 | |
| SCHEMBL6107774 | 0.82 | MCHR1 (0.88) | MCHR1MCHR2 | |
| SCHEMBL14454759 | 0.81 | HPGD (0.66) | MCHR1EPHX2POLBMEN1KMT2A | |
| SCHEMBL6152168 | 0.81 | EPHX2 (0.68) | MCHR1MCHR2EPHX2RAF1NAMPT | |
| SCHEMBL18502046 | 0.81 | HRH3 (0.62) | MCHR1MCHR2POLBGLAL3MBTL1 | |
| SCHEMBL5409909 | 0.81 | MCHR1 (0.56) | MCHR1MCHR2EPHX2RAF1POLB | |
| SCHEMBL4502913 | 0.80 | CYP1A2 (0.73) | POLBMEN1KMT2AGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087044-A2 | NOVEL CARBOXAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |