Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.68 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.57 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.57 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | FPR3 | P25089 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112404 | 0.85 | MCHR1 (0.81) | EPHX2MCHR1MCHR2RAF1MAPT | |
| SCHEMBL14430801 | 0.83 | EPHX2 (0.61) | EPHX2NAMPTMAPTGAAMAPK1 | |
| SCHEMBL6110588 | 0.82 | MCHR1 (0.77) | EPHX2MCHR1MCHR2MAPT | |
| SCHEMBL7255752 | 0.81 | MCHR1 (0.79) | EPHX2MCHR1MCHR2RAF1NAMPT | |
| SCHEMBL5483156 | 0.81 | SCN9A (0.59) | NAMPTMAPTGAAMAPK1 | |
| SCHEMBL20805845 | 0.81 | EPHX2 (0.67) | EPHX2MCHR1RAF1FAAHNAMPT | |
| SCHEMBL6110772 | 0.80 | MCHR1 (0.81) | EPHX2MCHR1MCHR2RAF1 | |
| SCHEMBL14430677 | 0.80 | CHRM4 (0.62) | MCHR1MCHR2NAMPTMAPT | |
| SCHEMBL6110339 | 0.80 | MCHR1 (0.78) | EPHX2MCHR1MCHR2MAPT | |
| SCHEMBL5477139 | 0.79 | GLA (0.59) | NAMPTMAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497260-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM Pharma A/S (DK) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087045-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |