Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KAT7 | O95251 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400311 | 0.92 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2ABACE1 | |
| SCHEMBL32687619 | 0.91 | NR1H2 (0.47) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL7260840 | 0.91 | NR1H2 (0.47) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL343699 | 0.91 | NR1H2 (0.47) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL23325142 | 0.88 | MEN1 (0.54) | MEN1ALDH1A1MAPTKMT2ABACE1 | |
| SCHEMBL20268177 | 0.88 | MEN1 (0.54) | MEN1ALDH1A1MAPTKMT2ABACE1 | |
| SCHEMBL2070126 | 0.88 | MEN1 (0.54) | MEN1ALDH1A1MAPTKMT2ABACE1 | |
| SCHEMBL6407123 | 0.87 | MEN1 (0.53) | MEN1ALDH1A1MAPTKMT2ABACE1 | |
| SCHEMBL771181 | 0.87 | MEN1 (0.53) | MEN1ALDH1A1MAPTKMT2ABACE1 | |
| SCHEMBL12844406 | 0.87 | ALDH1A1 (0.53) | MEN1ALDH1A1MAPTKMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013526-A1 | ANTICOAGULANT COMPOUNDS | MERCK & CO. INC. (US) | 2003-02-20 | — | — | WO | disclosed |