Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 16/20 | 0.50 |
| ▸ | PPARA | Q07869 | 15/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101120 | 0.92 | PPARG (0.53) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL5100503 | 0.91 | LMNA (0.54) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL5081077 | 0.89 | PPARG (0.63) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL7255050 | 0.89 | PPARG (0.63) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL14265747 | 0.89 | PPARG (0.63) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL5108315 | 0.88 | LMNA (0.53) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL7261636 | 0.87 | MAPT (0.52) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL5107699 | 0.87 | LMNA (0.54) | LMNATP53MAPTPPARGPPARA | |
| SCHEMBL5112858 | 0.84 | LMNA (0.46) | LMNATP53MAPTPPARGPPARA | |
| Tromethamine SCHEMBL7525169 | 0.84 | PPARG (0.56) | LMNATP53MAPTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024944-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BICYCLIC ANTIDIABETIC COMPOUNDS | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-03-27 | — | — | WO | disclosed |