Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.75 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884124 | 1.00 | MCHR1 (0.75) | MCHR1FFAR1ROCK2DRD4DRD3 | |
| SCHEMBL5884214 | 0.86 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL5883841 | 0.86 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL7260093 | 0.86 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL7259172 | 0.83 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL5884140 | 0.83 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL5883856 | 0.81 | MCHR1 (0.88) | MCHR1 | |
| SCHEMBL5884277 | 0.80 | MCHR1 (0.90) | MCHR1 | |
| SCHEMBL5884440 | 0.80 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL5884259 | 0.80 | MCHR1 (0.76) | MCHR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003105850-A1 | 2-AMINOQUINOLINES AS MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2003-12-24 | — | — | WO | claimed |
| WO-2003105850-A1 | 2-AMINOQUINOLINES AS MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2003-12-24 | — | — | WO | disclosed |