SCHEMBL7259172

SCHEMBL7259172

CC(C)(C)c1ccc(CN2CCC(Oc3cccc4ccc(N)nc34)C2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5884140 1.00 MCHR1 (1.00) MCHR1
SCHEMBL5884214 0.88 MCHR1 (1.00) MCHR1
SCHEMBL5883841 0.88 MCHR1 (1.00) MCHR1
SCHEMBL7260093 0.88 MCHR1 (1.00) MCHR1
SCHEMBL5883856 0.86 MCHR1 (0.88) MCHR1
SCHEMBL7256286 0.83 MCHR1 (0.75) MCHR1
SCHEMBL5884124 0.83 MCHR1 (0.75) MCHR1
SCHEMBL5884310 0.81 MCHR1 (0.87) MCHR1
SCHEMBL5884277 0.80 MCHR1 (0.90) MCHR1
SCHEMBL5884440 0.80 MCHR1 (1.00) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003105850-A1 2-AMINOQUINOLINES AS MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS ABBOTT LABORATORIES (US) 2003-12-24 WO claimed
WO-2003105850-A1 2-AMINOQUINOLINES AS MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS ABBOTT LABORATORIES (US) 2003-12-24 WO disclosed