Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.69 |
| ▸ | HTR2C | P28335 | 13/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.69 |
| ▸ | DRD2 | P14416 | 7/20 | 0.69 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588947 | 0.95 | HTR2A (0.77) | HTR2AHTR2CKCNH2DRD2EPHX2 | |
| Methyl Benzoate SCHEMBL7256335 | 0.90 | HTR2A (0.59) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL6585510 | 0.90 | HTR2A (0.83) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL6587204 | 0.86 | HTR2A (0.78) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL5210193 | 0.82 | HTR2A (1.00) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL6586349 | 0.80 | HTR2A (0.75) | HTR2AHTR2CKCNH2DRD2EPHX2 | |
| SCHEMBL6589393 | 0.78 | HTR2A (0.87) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL6588137 | 0.78 | HTR2A (1.00) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL6586480 | 0.76 | HTR2A (0.78) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL6586485 | 0.75 | HTR2A (1.00) | HTR2AHTR2CKCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203889-A1 | Phenylsulphonyl derivatives as 5-HT receptor ligands | MERCK & CO., INC. | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203889-A1 | Phenylsulphonyl derivatives as 5-HT receptor ligands | HTR2A, HTR5A, HTR2C | HTR2A 1/4885HTR2C 3/4885KCNH2 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.