Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739841 | 0.86 | KMT2A (0.47) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL21059189 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL21059187 | 0.81 | L3MBTL1 (0.63) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL21059246 | 0.80 | L3MBTL1 (0.62) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL7378894 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL13506223 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL3867996 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL21771948 | 0.78 | GAA (0.55) | SMN1; SMN2CYP2C19ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL27596581 | 0.78 | HSD17B10 (0.68) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1HPGD | |
| SCHEMBL6802645 | 0.78 | HSD17B10 (0.46) | SMN1; SMN2KMT2AL3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003093247-A2 | ANTIBACTERIAL AGENTS | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-11-13 | — | — | WO | disclosed |