⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725791 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL4947043 | 0.67 | — | — | |
| SCHEMBL902714 | 0.67 | — | — | |
| SCHEMBL8763382 | 0.67 | — | — | |
| SCHEMBL2686899 | 0.65 | — | — | |
| SCHEMBL8762215 | 0.62 | ALDH1A1 (0.32) | — | |
| SCHEMBL2012613 | 0.61 | — | — | |
| SCHEMBL2167407 | 0.61 | — | — | |
| SCHEMBL13860417 | 0.61 | — | — | |
| Propane SCHEMBL29000738 | 0.59 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549120-B | Method for preparing ribonucleoside | 吉利德科学公司 | 2025-04-29 | — | — | CN | claimed |
| CN-118994170-A | Process for preparing 1' -cyanonucleosides | 吉利德科学公司 | 2024-11-22 | — | — | CN | claimed |
| WO-2024177249-A1 | PHOTOVOLTAIC THERMAL REGENERATION SYSTEM AND OPERATING METHOD THEREFOR | 삼성전자 주식회사 | 2024-08-29 | — | — | WO | claimed |
| CN-115298181-B | Process for preparing 1' -cyanonucleosides | 吉利德科学公司 | 2024-08-16 | — | — | CN | claimed |
| WO-2022256490-A9 | IMPROVED SYNTHESIS OF PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | Antios Therapeutics, Inc. (US) | 2023-08-17 | — | — | WO | claimed |
| US-11613553-B2 | Methods of preparing 1′-cyano nucleosides | GILEAD SCIENCES, INC. (US) | 2023-03-28 | — | — | US | claimed |
| EP-4118085-A2 | METHODS OF PREPARING 1'-CYANO NUCLEOSIDES | GILEAD SCIENCES, INC. (US) | 2023-01-18 | — | — | EP | claimed |
| WO-2022256490-A2 | IMPROVED SYNTHESIS OF PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | Antios Therapeutics, Inc. (US) | 2022-12-08 | — | — | WO | claimed |
| CN-115298181-A | Process for preparing 1' -cyanonucleosides | 吉利德科学公司 | 2022-11-04 | — | — | CN | claimed |
| CN-111233869-B | Novel compound for preparing Rudexilvir key intermediate and preparation method thereof | 杭州新博思生物医药有限公司 | 2022-09-16 | — | — | CN | claimed |
| US-20210309689-A1 | METHODS OF PREPARING 1'-CYANO NUCLEOSIDES | GILEAD SCIENCES, INC. | 2021-10-07 | — | — | US | claimed |
| WO-2021183750-A2 | METHODS OF PREPARING 1'-CYANO NUCLEOSIDES | GILEAD SCIENCES, INC. (US) | 2021-09-16 | — | — | WO | claimed |
| CN-106414414-B | Process for producing trione compound | 组合化学工业株式会社 | 2020-07-14 | — | — | CN | claimed |
| US-9850198-B2 | Process for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds | GRUENENTHAL GMBH (DE) | 2017-12-26 | — | — | US | claimed |
| US-20030119659-A1 | Ligands and asymmetric catalysts made by using the same | JAPAN AS REPRESENTED BY PRESIDENT OF THE UNIVERSITY OF TOKYO (JP) | 2003-06-26 | — | — | US | claimed |
| EP-4591935-A2 | METHODS FOR THE PREPARATION OF RIBOSIDES | Gilead Sciences, Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| CN-113549120-B | Method for preparing ribonucleoside | 吉利德科学公司 | 2025-04-29 | — | — | CN | disclosed |
| EP-0415166-A2 | Process for the preparation of cyanohydantoines | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4957540-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0349195-A2 | Direct synthesis by cationic polymerization of nitrogen-containing polymers | EXXON CHEMICAL PATENTS INC. (US) | 1990-01-03 | — | — | EP | disclosed |