Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135295 | 0.98 | CA1 (0.48) | CA1CA2POLBKMT2AFKBP1A | |
| SCHEMBL4455223 | 0.87 | PTPRB (0.48) | CA1CA2KMT2AALDH1A1PKM | |
| SCHEMBL24732420 | 0.80 | CA1 (0.53) | CA1CA2POLBKMT2AFKBP1A | |
| SCHEMBL4591628 | 0.78 | CA1 (0.64) | CA1CA2POLBKMT2AALDH1A1 | |
| SCHEMBL21033855 | 0.78 | CA1 (0.52) | CA1CA2POLBKMT2AFKBP1A | |
| SCHEMBL7863309 | 0.76 | PTPRB (0.42) | CA1CA2ALDH1A1CYP3A4CA12 | |
| SCHEMBL3041175 | 0.76 | CA1 (0.52) | CA1CA2KMT2AALDH1A1CYP3A4 | |
| SCHEMBL1230858 | 0.76 | KEAP1 (0.53) | CA1CA2POLBKMT2AALDH1A1 | |
| SCHEMBL3088460 | 0.76 | CA1 (0.61) | CA1CA2KMT2AALDH1A1MAPK1 | |
| SCHEMBL1122831 | 0.76 | CA1 (0.61) | CA1CA2KMT2AFKBP1AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |