Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627629 | 0.94 | HPGD (0.76) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL28146850 | 0.89 | NPSR1 (0.56) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL69310 | 0.87 | HPGD (1.00) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL7253527 | 0.85 | ALDH1A1 (0.78) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL7252897 | 0.82 | HPGD (0.83) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL14236103 | 0.81 | NPSR1 (0.70) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL1450411 | 0.80 | HPGD (0.80) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL5203823 | 0.80 | ALDH1A1 (1.00) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL11829885 | 0.80 | ALDH1A1 (1.00) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL3131054 | 0.80 | ALDH1A1 (0.78) | HPGDALDH1A1MAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035614-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |