Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29828929 | 0.82 | CTNNB1 (0.55) | CYP3A4SMN1; SMN2ALDH1A1MAPK1CTNNB1 | |
| SCHEMBL5391668 | 0.82 | CTNNB1 (0.55) | CYP3A4SMN1; SMN2ALDH1A1MAPK1CTNNB1 | |
| SCHEMBL7668928 | 0.80 | MAPT (0.50) | NPC1RAB9ACYP3A4SMN1; SMN2CASP3 | |
| SCHEMBL773047 | 0.80 | KDM4E (0.51) | CYP3A4SMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL23643822 | 0.76 | ALDH1A1 (0.44) | NPC1RAB9ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8569388 | 0.76 | KDM4E (0.54) | NPC1RAB9AADRB2ADRB1ADRB3 | |
| SCHEMBL28568470 | 0.76 | KDM4E (0.50) | NPC1RAB9ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL2268770 | 0.75 | CYP3A4 (0.56) | NPC1RAB9ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL23511720 | 0.75 | ALDH1A1 (0.52) | CYP3A4ALDH1A1MAPK1PARP1TSHR | |
| SCHEMBL24163158 | 0.73 | HPGD (0.58) | NPC1RAB9ACYP3A4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067935-B1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1067935-A4 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1067935-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | The Regents of the University of California (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6124278-A | COGNITION ACTIVATORS FOR LEARNING/MEMORY ENHANCEMENT AND TREATMENT OF BRAIN/PSYCHOLOGICAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999051240-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-10-14 | — | — | WO | disclosed |