Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.56 |
| ▸ | CYCS | P99999 | 4/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262340 | 0.83 | TOP1 (0.53) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL13609840 | 0.82 | TOP1 (0.56) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL31019566 | 0.82 | TOP1 (0.52) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL2403632 | 0.79 | TOP1 (0.54) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL10523963 | 0.79 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL10730297 | 0.79 | MEN1 (0.57) | TOP1CYCSABCG2ENPP2 | |
| Acetic Acid SCHEMBL9639956 | 0.78 | TOP1 (0.67) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL30136 | 0.78 | TOP1 (0.64) | TOP1CYCSENPP2STAT3STAT1 | |
| SCHEMBL29405434 | 0.78 | TOP1 (0.64) | TOP1CYCSENPP2STAT3STAT1 | |
| SCHEMBL25395869 | 0.77 | TOP1 (0.91) | TOP1CYCSABCG2ENPP2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891977-B1 | 5-(4-Hydroxyphenyl)-porphyrin derivatives as photosensitisers | DLR EV (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6107480-A | 5-(HYDROXYLATEDPHENYL) PORPHYRIN DERIVATIVES WHICH MAY BE COVALENTLY BONDED TO SPECIFIED POLYMERS VIA THE HYDROXYLATED PHENYL GROUP; USE AS PHOTOSENSITIZERS FOR THE CATALYTIC FORMATION OF SINGLET OXYGEN | DLR, DEUTSCHE ZENTRUM FUR LUFT UND RAUMFAHRT E.V. (DE) | 2000-08-22 | — | — | US | disclosed |
| EP-0891977-A1 | 5-(4-Hydroxyphenyl)-porphyrin derivatives as photosensitisers | DLR Deutsches Zentrum für Luft- und Raumfahrt e.V. (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1993000815-A1 | POLYMER COMPOSITIONS | COURTAULDS PLC (GB) | 1993-01-21 | — | — | WO | disclosed |