Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.54 |
| ▸ | CYCS | P99999 | 4/20 | 0.53 |
| ▸ | TGM2 | P21980 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609844 | 0.82 | TOP1 (0.53) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL16923748 | 0.81 | ALDH1A1 (0.55) | TOP1CYCSABCG2ENPP2KDM4E | |
| SCHEMBL16912677 | 0.81 | TOP1 (0.54) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL8572426 | 0.80 | TOP1 (0.53) | TOP1CYCSABCG2MAPT | |
| SCHEMBL7258251 | 0.79 | TOP1 (0.56) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL16920374 | 0.78 | SMN1; SMN2 (0.54) | TOP1CYCSABCG2KDM4EALDH1A1 | |
| SCHEMBL8994447 | 0.78 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2KDM4E | |
| Acetic Acid SCHEMBL9639956 | 0.77 | TOP1 (0.67) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL1383664 | 0.77 | TGM2 (0.78) | TGM2FYNSRCVCPKDM4E | |
| SCHEMBL30136 | 0.77 | TOP1 (0.64) | TOP1CYCSENPP2STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227159-B1 | Toner compositions and processes | XEROX CORPORATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-8227163-B2 | Coated carriers | XEROX CORPORATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20110236815-A1 | COATED CARRIERS | XEROX CORPORATION (US) | 2011-09-29 | — | — | US | disclosed |