Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424482 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL28300061 | 0.84 | ALDH1A1 (0.46) | MAPK1TSHRALDH1A1GAAPKM | |
| SCHEMBL48262 | 0.79 | MAPK1 (0.52) | MAPK1TSHRALDH1A1GAARECQL | |
| SCHEMBL7666103 | 0.77 | MAPK1 (0.50) | MAPK1TSHRALDH1A1GAARECQL | |
| SCHEMBL13204921 | 0.77 | MAPK1 (0.50) | MAPK1TSHRALDH1A1GAAPKM | |
| SCHEMBL2420634 | 0.77 | CA1 (0.58) | MAPK1TSHRALDH1A1PKMCA12 | |
| SCHEMBL16325344 | 0.77 | FNTA (0.41) | MAPK1TSHRALDH1A1KDM4ECA12 | |
| SCHEMBL29229351 | 0.77 | GRIA1 (0.42) | ALDH1A1PKMSMN1; SMN2KDM4ECA12 | |
| SCHEMBL27182941 | 0.76 | MAPK1 (0.49) | MAPK1TSHRALDH1A1GAARECQL | |
| SCHEMBL15498660 | 0.74 | GRIA1 (0.65) | MAPK1TSHRALDH1A1GAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |
| US-4104298-A | FROM SULFAMIC ACIDS AND PHOSPHORUS PENTAHALIDES | BASF AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |