Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291814 | 0.81 | LMNA (0.48) | TAAR1ALDH1A1TRPV1CTSDBACE1 | |
| SCHEMBL10848449 | 0.80 | HTR2A (0.46) | TAAR1ALDH1A1MAPTHTTTSHR | |
| SCHEMBL11285044 | 0.80 | LMNA (0.47) | TAAR1ALDH1A1TRPV1CTSDBACE1 | |
| SCHEMBL11285051 | 0.78 | HTT (0.38) | TAAR1ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL5744441 | 0.76 | TAAR1 (0.38) | TAAR1ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL11862252 | 0.75 | MGAM (0.44) | TAAR1ALDH1A1MAPTGRIN2BHTR2A | |
| SCHEMBL11486948 | 0.75 | TRPV1 (0.43) | TAAR1TRPV1CTSDBACE1LMNA | |
| SCHEMBL924430 | 0.74 | BACE1 (0.55) | TRPV1CTSDBACE1BACE2 | |
| SCHEMBL924428 | 0.74 | BACE1 (0.55) | TRPV1CTSDBACE1BACE2 | |
| SCHEMBL27700171 | 0.74 | TRPV1 (0.47) | TAAR1ALDH1A1MAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003014113-A1 | NOVEL BENZOPYRAN COMPOUNDS AND PROCESS FOR THEIR PREPARATION AND USE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2003-02-20 | — | — | WO | disclosed |