SCHEMBL725848

SCHEMBL725848

Cc1cc(C)c(N(C)C)cc1C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
ESR1 P03372 1/20 0.33
GAA P10253 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
MAOA P21397 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7930504 0.97 CYP3A4 (0.35) TSHRCYP3A4MAPK1ESR1GAA
SCHEMBL9094447 0.94 ESR1 (0.35) TSHRCYP3A4MAPK1ESR1GAA
SCHEMBL20210283 0.81 CYP3A4 (0.36) TSHRCYP3A4MAPK1
SCHEMBL10111200 0.78 BCHE (0.31) TSHRESR1MAPT
SCHEMBL26281354 0.78 GAA (0.37) CYP3A4ESR1GAAMAPTKMT2A
SCHEMBL533174 0.78 CYP3A4 (0.55) TSHRCYP3A4MAPK1GAAMAPT
SCHEMBL9403425 0.78 CYP3A4 (0.55) TSHRCYP3A4MAPK1GAAMAPT
SCHEMBL15760671 0.75 ESR1 (0.32) ESR1
SCHEMBL20457103 0.75 ALDH1A1 (0.36) ESR1GAA
SCHEMBL13584369 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1709085-B1 SUPPORTED ACTIVATOR FOR POLYMERISATION CATALYST EXXONMOBIL CHEM PATENTS INC (US) 2013-03-20 EP claimed
JP-4751836-B2 2011-08-17 JP claimed
US-7220695-B2 Supported activator EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US claimed
EP-1709085-A2 SUPPORTED ACTIVATOR ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2006-10-11 EP claimed
WO-2005068515-A2 SUPPORTED ACTIVATOR FOR POLYMERISATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-07-28 WO claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
US-5830820-A Olefin polymerization catalyst and olefin polymerization process TOSOH CORPORATION (JP) 1998-11-03 US claimed
EP-0658576-B1 Olefin polymerization catalyst and olefin polymerization process TOSOH CORP (JP) 1998-07-29 EP claimed
US-20230399420-A1 CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-12-14 US disclosed
WO-2023239560-A1 CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATON, U.S.A. (US) 2023-12-14 WO disclosed
US-20220144978-A1 METHOD FOR PRODUCING CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2022-05-12 US disclosed
EP-3950734-A1 PRODUCTION METHOD FOR CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2022-02-09 EP disclosed
EP-3353217-A1 POLYMERIZATION PROCESS USING PYRIDYLDIAMIDO COMPOUNDS SUPPORTED ON ORGANOALUMINUM TREATED LAYERED SILICATE SUPPORTS ExxonMobil Chemical Patents Inc. (US) 2018-08-01 EP disclosed
US-9994657-B2 Polymerization process using bis phenolate compounds supported on organoaluminum treated layered silicate supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-06-12 US disclosed
EP-0619326-B1 Olefin polymerization catalyst and olefin polymerisation process TOSOH CORP (JP) 1997-06-25 EP disclosed
EP-0775707-A1 IONIC COMPOUNDS AND CATALYST FOR OLEFIN POLYMERIZATION USING THE COMPOUNDS SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-05-28 EP disclosed
EP-0727443-A1 Catalyst for olefin polymerization and process for producing olefin polymers Tosoh Corporation (JP) 1996-08-21 EP disclosed
EP-0658576-A1 Olefin polymerization catalyst and olefin polymerization process Tosoh Corporation (JP) 1995-06-21 EP disclosed
EP-0628574-A1 Olefin polymerization catalyst and olefin polymerization process TOSOH CORPORATION (JP) 1994-12-14 EP disclosed
EP-0619326-A1 Olefin polymerization catalyst and olefin polymerisation process TOSOH CORPORATION (JP) 1994-10-12 EP disclosed