Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455902 | 0.90 | KDM4E (0.50) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL7456376 | 0.83 | KDM4E (0.48) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL7357438 | 0.80 | KDM4E (0.46) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL24866430 | 0.77 | KDM4E (0.51) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL15219972 | 0.77 | KDM4E (0.51) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL9046684 | 0.75 | KDM4E (0.50) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL72244 | 0.75 | KDM4E (0.50) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL9044947 | 0.75 | KDM4E (0.50) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| SCHEMBL422525 | 0.74 | KDM4E (0.49) | KDM4ERAB9ANPC1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL8907355 | 0.74 | KDM4E (0.49) | KDM4ERAB9ANPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299395-A1 | OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-09 | — | — | EP | claimed |
| WO-2002004462-A1 | OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-17 | — | — | WO | claimed |