Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21382381 | 0.92 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2D6GAALMNA | |
| SCHEMBL13057587 | 0.92 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2D6GAAKMT2A | |
| SCHEMBL21382380 | 0.92 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2D6GAALMNA | |
| SCHEMBL1816937 | 0.90 | CYP1A2 (0.62) | ALDH1A1CYP1A2CYP2D6GAALMNA | |
| SCHEMBL1816934 | 0.90 | CYP1A2 (0.62) | ALDH1A1CYP1A2CYP2D6GAALMNA | |
| SCHEMBL11294244 | 0.90 | CYP1A2 (0.62) | ALDH1A1CYP1A2CYP2D6GAAKMT2A | |
| SCHEMBL5423672 | 0.90 | CYP1A2 (0.62) | ALDH1A1CYP1A2CYP2D6GAALMNA | |
| SCHEMBL1849659 | 0.89 | ALDH1A1 (0.77) | ALDH1A1CYP1A2CYP2D6LMNAKMT2A | |
| SCHEMBL4530301 | 0.89 | ALDH1A1 (0.77) | ALDH1A1CYP1A2CYP2D6LMNAKMT2A | |
| SCHEMBL1325867 | 0.89 | ALDH1A1 (0.77) | ALDH1A1CYP1A2CYP2D6LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372892-B2 | Attached, high reactivity rigid polyurethane foams | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-12 | — | — | US | claimed |
| EP-1725600-B2 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-10-03 | — | — | EP | claimed |
| JP-4824670-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| EP-1725600-B1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-09-03 | — | — | EP | claimed |
| US-20080038461-A1 | Attached, High Reactivity Rigid Polyurethane Foams | DOW GLOBAL TECHNOLOGIES LLC | 2008-02-14 | — | — | US | claimed |
| JP-2007528434-A | — | — | 2007-10-11 | — | — | JP | claimed |
| EP-1725600-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | The Dow Global Technologies Inc. (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005090431-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2005-09-29 | — | — | WO | claimed |
| EP-1924619-B1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS CONTAINING OXAZOLIDONE GROUPS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-11-19 | — | — | EP | disclosed |
| US-8372892-B2 | Attached, high reactivity rigid polyurethane foams | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-12 | — | — | US | disclosed |
| EP-1725600-B2 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-10-03 | — | — | EP | disclosed |
| US-7714030-B2 | Attached, high reactivity rigid polyurethane foams containing oxazolidone groups | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-05-11 | — | — | US | disclosed |
| EP-1725600-B1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1924619-A1 | ATTACHED, HIGH REACTIVITY RIGID POLYURETHANE FOAMS CONTAINING OXAZOLIDONE GROUPS | The Dow Global Technologies Inc. (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-0236895-A2 | Process for preparing a cellular polyurethane | BAYER AG (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4677136-A | MOLDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0204141-A2 | USE OF UREA AND/OR BIURET GROUPS CONTAINING POLYISOCYANATES AS ISOCYANATE COMPONENT IN THE PREPARATION OF PLASTICS BY THE REACTION INJECTION MOLDING PROCESS | BAYER AG (DE) | 1986-12-10 | — | — | EP | disclosed |
| US-4500656-A | CONTAINING LIQUID ADDUT OF AMINE AND CARBON DIOXIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0121850-A2 | Process for preparing a cellular polyurethane | BAYER AG (DE) | 1984-10-17 | — | — | EP | disclosed |
| US-4469856-A | Non-crystalline polyamine/carbonic acid salt compositions, a process for their preparation and their use for the production of polyurethane ureas, especially foamed coatings | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-04 | — | — | US | disclosed |