Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | NPR3 | P17342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103680 | 1.00 | ITGB1 (0.48) | ITGB1ITGA4APPNPR3 | |
| SCHEMBL7103805 | 0.92 | ITGB1 (0.54) | ITGB1ITGA4APPNPR3 | |
| SCHEMBL7103802 | 0.92 | ITGB1 (0.54) | ITGB1ITGA4APPNPR3 | |
| SCHEMBL7103715 | 0.90 | ITGB1 (0.60) | ITGB1ITGA4APPNPR3 | |
| SCHEMBL7103720 | 0.90 | ITGB1 (0.60) | ITGB1ITGA4APPNPR3 | |
| SCHEMBL7259476 | 0.88 | ITGB1 (0.56) | ITGB1ITGA4APP | |
| SCHEMBL7105086 | 0.88 | ITGB1 (0.56) | ITGB1ITGA4APP | |
| SCHEMBL7264602 | 0.87 | ITGB1 (0.56) | ITGB1ITGA4APP | |
| SCHEMBL7264611 | 0.87 | ITGB1 (0.56) | ITGB1ITGA4APP | |
| SCHEMBL7103647 | 0.87 | ITGB1 (0.55) | ITGB1ITGA4NPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518283-B1 | To modify integrin function in such a way as to beneficially modulate cell adhesion | CELLTECH R&D LIMITED (GB) | 2003-02-11 | — | — | US | disclosed |