Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | NADK | O95544 | 2/20 | 0.67 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | AMD1 | P17707 | 4/20 | 0.59 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.57 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835108 | 0.91 | GAPDH (0.84) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL7258959 | 0.85 | GAPDH (0.69) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL1106676 | 0.82 | GAPDH (1.00) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL1097451 | 0.82 | GAPDH (1.00) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL15906322 | 0.82 | GAPDH (1.00) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL1097445 | 0.82 | GAPDH (1.00) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL1099269 | 0.81 | GAPDH (0.83) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL952181 | 0.81 | GAPDH (0.83) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL1099264 | 0.81 | GAPDH (0.83) | GAPDHHSD17B10NADKSIRT2SIRT1 | |
| SCHEMBL952182 | 0.81 | GAPDH (0.83) | GAPDHHSD17B10NADKSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |